Portfolio Manager, Life Sciences

About NATi

The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform dedicated to advancing RNA-based medicines and revolutionizing drug and vaccine development. NATi's mission is to establish Singapore as a globally recognized hub of excellence in nucleic acid therapeutics research, clinical translation, and commercialization.

Position Overview

We are seeking a highly agile and strategic Portfolio Manager, Life Sciences with experience in venture capital, consulting, biotech and/or drug development. The successful candidate will play a central role in shaping, managing, and advancing a diverse portfolio of life science assets and initiatives, from early discovery through translational and commercial inflection points.

Key Responsibilities

• Lead end to end portfolio management across multiple biotech and therapeutic programs
• Conduct commercial due diligence for new investment opportunities
• Develop and execute IP strategies
• Act as a key interface between internal teams and external stakeholders
• Experience in grant strategy and management

Required Skills & Competencies

Highly agile, adaptable, and comfortable operating in ambiguity. Strong strategic thinker with the ability to move seamlessly between high level vision and detailed execution. Credible communicator able to translate complex science into clear commercial and strategic narratives. Collaborative, proactive, and outcome-oriented, with a strong sense of ownership.

Qualifications & Experience

PhD in a relevant life sciences discipline (e.g. biomedical sciences, pharmacology, molecular biology, bioengineering, or related field). Significant experience across venture capital, consulting, biotech, pharma, or drug development, with exposure to asset-centric decision making. Proven track record in commercial due diligence, portfolio analysis, and strategic evaluation of life science assets. Hands-on experience with intellectual property strategy in a biotech or translational context. Demonstrated capability in stakeholder management across academia, industry, investors, and public sector funders. Experience managing or supporting grant-funded programs and complex funding structures. [Not required but preferable] prior experience in ophthalmology or eye-related indications (drug, device, or platform-based). [Not required but preferable] exposure to company formation, spin-outs, licensing, or strategic partnerships.